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February 10, 1945

Current Comment

JAMA. 1945;127(6):334. doi:10.1001/jama.1945.02860060032012

PEPTIC ULCERATION IN GASTRIC CARCINOMA  Ulceration apparently of peptic nature is not infrequent in gastric carcinoma.1 At times such ulceration may present many features characteristic of simple ulcer, including reparative processes. Carefully studied cases of this nature have been reported recently by Eusterman,2 Palmer and Humphreys3 and others. In each of Eusterman's 5 cases a small carcinoma, roentgenologically indistinguishable from simple ulcer, apparently healed completely under intensive medical treatment. The 4 cases described in detail by Palmer and Humphreys simulated simple ulcer in many respects at the same time as they presented diagnostic signs of carcinoma. In these cases the ulcers had the morphologic characteristics of simple ulcer with more or less well defined repair of the defects and carcinomatous infiltration of the walls. In none of these cases was there definite clinical evidence of preexisting simple ulcer. The cases mentioned illustrate difficulties in the way of