[Skip to Navigation]
Sign In
Evolving Issues in Oncology
March 18, 2019

The Surprisingly Positive Association Between Obesity and Cancer Immunotherapy Efficacy

Author Affiliations
  • 1Department of Dermatology, University of California Davis School of Medicine, Sacramento
  • 2Division of Hematology/Oncology, Department of Internal Medicine, University of California Davis School of Medicine, Sacramento
  • 3Department of Medicine, Harvard Medical School, Boston, Massachusetts
JAMA. 2019;321(13):1247-1248. doi:10.1001/jama.2019.0463

Of all the physiological parameters affecting human health, few have generated such an overwhelming consensus of adverse effects as obesity (typically defined as having a body mass index [BMI] ≥30). The incidence of obesity has been steadily rising in developed countries, reaching pandemic proportions, with a prevalence of more than 39% in the United States and continuing to increase.1 It is therefore critical to understand the potential effects of obesity on disease incidence and progression and on treatment outcomes.

Add or change institution