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To the Editor:—
In The Journal, Oct. 21, 1944, page 472, is an article entitled "Male Climacteric" by Heller and Meyers. Under "Results of the Therapeutic Test in Patients with High Gonadotropins (Group B)" the authors state that "on resumption of the therapy with testosterone propionate relief of symptoms was again afforded and sexual potency returned. Thus the specificity of therapy was established." This statement is not entirely true. It is admitted that testosterone can produce such a result, but so can estradiol and diethylstilbestrol, for I have been able to study personally three men so treated. Consequently, testosterone propionate is not proved to be a specific for the male climacteric.The authors list pruritus as a psychic symptom. The pruritus that one sometimes sees with the climacteric, male or female, is a definite deficiency disease syndrome and is far from psychic in the general sense of the word. Actually
Abarbanel AR. "MALE CLIMACTERIC". JAMA. 1945;127(7):419. doi:10.1001/jama.1945.02860070051022
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