In a historic case, a patient in London achieved sustained HIV remission after receiving an allogeneic hematopoietic stem cell transplant (HSCT) for Hodgkin lymphoma. The report, published in Nature, comes more than a decade after the now-famous “Berlin patient,” Timothy Ray Brown, was cured of HIV after 2 allogeneic HSCTs for acute myeloid leukemia. Both patients received cells from donors with a mutation in the CCR5 gene that provides resistance to HIV. Since Brown, no other successful cases of sustained HIV remission after stem cell transplantation have been reported.
Abbasi J. HIV Remission After Hematopoietic Stem Cell Transplant. JAMA. 2019;321(14):1343. doi:10.1001/jama.2019.3460
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