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Research Letter
May 7, 2019

Prevalence of Alcoholic Fatty Liver Disease Among Adults in the United States, 2001-2016

Author Affiliations
  • 1Department of Medicine, Highland Hospital, Oakland, California
  • 2Division of Gastroenterology and Hepatology, University of South Dakota Sanford School of Medicine, Sioux Falls
JAMA. 2019;321(17):1723-1725. doi:10.1001/jama.2019.2276

Alcoholic liver disease (ALD), comprising a spectrum of diseases ranging from alcoholic fatty liver disease (AFLD) to advanced ALD (including alcoholic hepatitis, cirrhosis, and cirrhosis complications),1 is a leading cause of mortality in the United States, with nearly 250 000 deaths attributed to ALD in 2010.2,3 Overall US clinical burden of ALD remains unclear, perhaps because of lack of a definitive standard for identifying ALD. This study focused on the specific, more well-defined subset of AFLD to estimate national prevalence among US adults.