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JAMA Clinical Guidelines Synopsis
May 3, 2019

Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum Period

Author Affiliations
  • 1University of Chicago, Chicago, Illinois
JAMA. 2019;321(19):1928-1929. doi:10.1001/jama.2019.5321

Thyroid hormone production increases during pregnancy. Thyroid dysfunction is common during pregnancy, and both hyperthyroidism and hypothyroidism are associated with increased risk of adverse pregnancy and perinatal outcomes. Accurate assessment of thyroid status and management of thyroid dysfunction in pregnant women are crucial to optimize maternal-fetal outcomes.

The guideline development process was sponsored by the ATA as a planned revision of guidelines published in 2011.1 The ATA appointed a task force of specialists in diverse areas. Standardized data collection forms were used and a literature search was performed for each topic, relevant literature appraised, and recommendations generated. External peer review was obtained on key recommendations. The guidelines were funded by the ATA, but task force members received no funding from the ATA or industry (Table 1). Conflicts of interest were reviewed initially, yearly, and on completion of the guideline. One committee member with a potential conflict recused himself from review of relevant guideline sections.

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