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March 17, 1945

COORDINATED RESEARCH FOR THE TESTING OF ANTIMALARIAL DRUGS

JAMA. 1945;127(11):650-651. doi:10.1001/jama.1945.02860110030009

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Abstract

To the list of volunteers who have aided the advancement of medical science may now be added prisoners in three American penitentiaries. Civilian investigators, aided by grants of funds from the Committee on Medical Research of the Office of Scientific Research and Development, and members of the Army, Navy and Public Health Service have participated in the program. Since March 1944 over 100 prisoner volunteers in a United States penitentiary have been exposed to relapsing vivax malaria in final tests of potential antimalarial drugs prior to their use in the armed forces. Over 100 more volunteers in two other prisons have taken large doses of new drugs for long periods of time to determine whether or not the drugs may safely be used in the prevention and treatment of malaria. The three institutions in which the cooperation of the prisoners has made possible the continuing success of this most important

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