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JAMA Insights
Women's Health
May 9, 2019

Abnormal Uterine Bleeding in Reproductive-Age Women

Author Affiliations
  • 1Department of Obstetrics and Gynecology, University of Florida College of Medicine-Jacksonville
  • 2UF Southside Women’s Health, Jacksonville, Florida
JAMA. 2019;321(21):2126-2127. doi:10.1001/jama.2019.5248

Abnormal uterine bleeding (AUB) in reproductive-age women (defined as abnormal in duration, quantity, or timing) is experienced by approximtely one-third of all women throughout their lifetime, impairs quality of life, and can be effectively managed medically in most cases.1

To minimize confusion associated with previously used terms including menorrhagia and meno-metrorrhagia, the International Federation of Gynecology and Obstetrics introduced updated terminology for AUB in nonpregnant women in 2011. Heavy menstrual bleeding (HMB) refers to ovulatory (cyclic) bleeding exceeding 8 days’ duration or heavy enough to interfere with a woman’s quality of life, a pattern of AUB distinct from the irregular bleeding associated with ovulatory dysfunction (AUB-O).1

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