To the Editor Dr Busse and colleagues1 analyzed the weighted mean differences of pain intensity and physical function after treatment with opioids vs placebo for chronic noncancer pain from 69 trials. However, their outcomes did not meet best practices in the reporting of systematic reviews of chronic pain trials2 and are not helpful for clinical practice.
Häuser W, Tölle T, Moore A. Meta-analysis of Opioids for Chronic Pain. JAMA. 2019;321(19):1934–1935. doi:10.1001/jama.2019.2177
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