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October 24, 1936

HEREDITARY RESISTANCE TO TUBERCULOSIS

JAMA. 1936;107(17):1405-1406. doi:10.1001/jama.1936.02770430055025

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Abstract

To the Editor:—  In The Journal, August 15, page 471, Miller and Rappaport have elaborated on the theory of inherited resistance to tuberculosis in a manner difficult to accept. Of course it is well known that in this country the mortality from tuberculosis varies greatly among certain race groups, being high among the colored races, particularly the Negro, and relatively low among Jews and Italians. It is also well known that the mortality is unusually high in isolated race groups, such as South Sea islanders, that have come for the first time in contact with tuberculous infection. It would thus appear that those races which have been in contact with civilization and its concomitant tuberculosis over the longest period of time would be more resistant to the disease. The authors, in explaining how this hereditary resistance is brought about, say that the resistance "has thus become progressively increased by the

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