The FDA has approved the first vaccine to prevent disease caused by all 4 dengue virus serotypes. The vaccine is indicated only for children and teens aged 9 to 16 years living in endemic areas who have had a previous, laboratory-confirmed dengue infection.
Although dengue cases are rare in the continental United States, the disease is found regularly in American Samoa, Puerto Rico, Guam, the US Virgin Islands and in Latin America, Southeast Asia, and the Pacific Islands. More than one-third of the global population lives in areas at risk of infection; up to 400 million infections occur annually.
Voelker R. Dengue Vaccine Gets the Nod. JAMA. 2019;321(21):2066. doi:10.1001/jama.2019.6886
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