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June 3, 2019

Setting Positive End-Expiratory Pressure in Mechanically Ventilated Patients Undergoing Surgery

Author Affiliations
  • 1Centre Hospitalier Universitaire Clermont-Ferrand, Département de Médecine Périopératoire, Anesthésie et Réanimation, Clermont-Ferrand, France
JAMA. 2019;321(23):2285-2287. doi:10.1001/jama.2019.7540

What is the optimal level of positive end-expiratory pressure (PEEP) for patients receiving mechanical ventilation? Despite decades of investigations, this question continues to be discussed among researchers and clinicians with no clear answer, leaving bedside management uncertain. The concept of protecting the lung during mechanical ventilation is considered a fundamental approach for patients in the intensive care unit with acute respiratory distress syndrome (ARDS),1 and is now attracting increasing interest for patients without injured lungs both in the intensive care unit and in the operating room.2-4