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Comment & Response
June 18, 2019

Evaluation of Patients With a History of Penicillin Allergy

Author Affiliations
  • 1Schneider Children’s Medical Center of Israel, Tel Aviv University, Tel Aviv, Israel
JAMA. 2019;321(23):2366-2367. doi:10.1001/jama.2019.4534

To the Editor Dr Shenoy and colleagues1 encouraged physicians, not only allergists, to evaluate patients with penicillin allergy before deciding not to use penicillin or other β-lactam antibiotics. Their approach is supported by evidence that shows that true penicillin allergy is rare and that penicillin oral challenge is a safe and effective method to rule out penicillin allergy. Ruling out penicillin allergy serves as an important tool for antimicrobial stewardship.