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Comment & Response
June 25, 2019

Electroencephalography-Guided Anesthetic Administration and Postoperative Delirium

Author Affiliations
  • 1Department of Anesthesiology and Critical Care Medicine, University of New Mexico School of Medicine, Albuquerque
JAMA. 2019;321(24):2470. doi:10.1001/jama.2019.5157

To the Editor The Electroencephalography Guidance of Anesthesia to Alleviate Geriatric Syndromes (ENGAGES) trial found no effect on postoperative delirium when intraoperative anesthesia depth was guided by EEG waveforms and derived parameters.1 However, there are various confounders and methodological issues that may have affected the authors’ conclusions and study generalizability.