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Clinical Trials Update
June 25, 2019

Supplements Improve Insulin Sensitivity

JAMA. 2019;321(24):2396. doi:10.1001/jama.2019.8400

Overweight and obese adults had improved insulin sensitivity after taking dietary supplements of inulin-propionate ester (IPE) or a high-fermentable fiber, according to a study in Gut.

Twelve adults without diabetes who were overweight or obese received in random order 20 g per day of IPE; a high-fermentable fiber control (inulin); and a low-fermentable fiber control (cellulose). Participants took each supplement for 42 days.