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Medical News & Perspectives
July 3, 2019

Wide Interest in a Vitamin C Drug Cocktail for Sepsis Despite Lagging Evidence

JAMA. 2019;322(4):291-293. doi:10.1001/jama.2019.7936

Critical care medicine specialist Paul Marik, MD, has described himself as a “status quo destabilizer,” and probably nothing illustrates that designation better than the sepsis treatment known as the Marik protocol.

In the past 3½ years, Marik says, more than 1300 patients have received his eponymous therapy—a combination of intravenous high-dose vitamin C, corticosteroids, and thiamine—at Sentara Norfolk General Hospital in Virginia, where he oversees the general intensive care unit (ICU).

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