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April 21, 1945


JAMA. 1945;127(16):1075. doi:10.1001/jama.1945.02860160051019

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To the Editor:—  In Queries and Minor Notes in The Journal, February 24, the item "Effect on Syphilis of Penicillin Treatment for Gonorrhea" ends with the statement "There is no information as to the effect of 100,000 to 200,000 units of penicillin given in one day on the blood test of a patient with an already existing positive serologic reaction." While it concerns only one individual, the following case report is submitted in an effort to supply such information: F. A., a Negro aged 23, was admitted to the Kansas State Sanatorium for Tuberculosis on Feb. 2, 1944 with far advanced pulmonary tuberculosis involving the right lung. At the University of Kansas outpatient clinic he had had 4 plus Wassermann and Kahn reactions on Dec. 24, 1943 and had received six injections of neoarsphenamine. On admission to the sanatorium his Kolmer reaction was doubtful and Kahn reaction positive.On physical examination

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