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November 28, 1936

EXPERIENCES WITH AMMONIUM MANDELATE IN URINARY INFECTIONSA REPORT OF RESULTS OBTAINED IN SIXTEEN CASES OF VARIOUS TYPES OF INFECTIONS REGARDLESS OF THE EXISTING PATHOLOGIC CONDITION

JAMA. 1936;107(22):1800-1805. doi:10.1001/jama.1936.02770480032009
Abstract

The medical profession is occasionally presented with a new urinary antiseptic before sufficient time has elapsed to permit competent observers to test adequately its therapeutic results. For that reason some drugs are used indiscriminately in all types of urinary infection instead of being restricted to the specific infections for which they were originally intended. Through this practice they sometimes fall into disrepute because of seemingly poor results.

At the present time we are apparently on the threshold of another such possibility. Recently some well known research workers through a logical sequence of events and experiments have presented the medical profession with an oral medication that has given startling results in certain types of urinary infection. Yet it has not been sufficiently investigated by controlled clinical and laboratory study to warrant its general distribution and use under the unrestricted title of "urinary antiseptic." Such a general term will undoubtedly bring it

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