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May 19, 1945


JAMA. 1945;128(3):181-182. doi:10.1001/jama.1945.02860200021006

Recent published reports indicate that obstetric and diabetic clinics now agree that whereas the maternal mortality in diabetic pregnancies has been low fetal mortality has been high. The past fetal mortality rates have ranged from 30 to 60 per cent, depending on the length of pregnancy observed. If the study has been limited to the third trimester, the usual rate has been 30 per cent. If the entire period of pregnancy has been reported, it has been as high as 60 per cent.

The long period of observation of diabetic pregnancies by obstetricians and internists has revealed four salient abnormalities. These four abnormalities may be classified simply as first, maternal; second, obstetric; third, chemical, and fourth, fetal. My purpose in this discussion is to evaluate these abnormalities as they have occurred in a series of 181 consecutive diabetic pregnancies studied at our clinic between January 1936 and June 1944. In

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