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December 5, 1936


JAMA. 1936;107(23):1892-1893. doi:10.1001/jama.1936.02770490046015

Consideration of the effects of heat falls into two natural divisions; namely, the acute results of encountering high temperatures for short periods, and the effects of residence in tropical climates. Drinker,1 in a recent article, has discussed some of the physiologic aspects of encountering these two forms of heat. Sweat is an important element concerned in body response to high temperatures. Since sweat contains from 0.1 to 0.5 per cent of sodium chloride, a daily production of sweat of 7.5 liters, such as may occur under the influence of high temperatures, would mean a loss of approximately 22.5 Gm. of salt. Since the average normal excretion of salt in the urine is only about 12 Gm. in twenty-four hours, such a depletion of body chlorides probably would initiate most important physiologic events. Under such circumstances, therefore, it would be necessary to restore the normal salt-water ratio as rapidly as

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