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June 9, 1945

SINGLE INJECTION TREATMENT OF GONORRHEA WITH PENICILLIN IN BEESWAX-PEANUT OILRESULTS IN 175 CASES

JAMA. 1945;128(6):404-407. doi:10.1001/jama.1945.02860230008002
Abstract

In previous reports1 two of us have described a method for prolonging the action of calcium penicillin by suspending it in beeswax-peanut oil and have shown successful results attained in a small group of patients with gonorrhea by a single injection of this mixture.

Our purpose here is to give the results obtained in the treatment of 175 cases of gonorrhea in males by a single injection of penicillin beeswax-peanut oil. The excellent results in the treatment of gonorrhea with penicillin in saline solution and the various methods and schedules of utilization have been reported by others.2

In our first reports1 a suspension of penicillin beeswax-peanut oil was obtained by shaking the mixture for ten to fifteen minutes by hand. We have since used a mechanical blender, which has proved more efficient and practical for preparing larger quantities. It is necessary to emphasize that the preparation of

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