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June 23, 1945


JAMA. 1945;128(8):594-595. doi:10.1001/jama.1945.02860250040012

The nutritional state of the patient assumes an important role in curing disease. In both experimental and spontaneous tumors the influence of energy intake, fat consumption per se, protein content of the diet and deficiency of certain vitamins have been shown to influence the course of development of the tumor. Many investigations have shown that mere restriction of food consumption in animals will reduce the incidence of both spontaneous and artificially induced tumors. Tannenbaum1 has demonstrated with statistics gathered from the life insurance companies that an increased incidence of cancer occurs among persons who were overweight at the time the insurance policy was issued. On the basis of such evidence Potter2 has even advocated ample exercise and a minimum food consumption as a measure for the prevention of human cancer.

Recently Morris3 has shown that in mice on a restricted calory regimen, so that the weanlings did