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News From the Centers for Disease Control and Prevention
August 13, 2019

Tuberculin Antigen Shortage

JAMA. 2019;322(6):496. doi:10.1001/jama.2019.10855

The CDC recently warned clinicians of a potential 3- to 10- month shortage of Aplisol (tuberculin PPD), 1 of 2 tuberculin antigens approved by the US Food and Drug Administration for tuberculosis skin tests.

Par Pharmaceuticals, which manufactures the test, notified the CDC that they expect an interruption in the supply of 5-mL vials starting in June 2019 and 1-mL vials starting in November 2019 or sooner, according to the agency. Updated information about the supply of the drug will be posted on the FDA’s website.