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JAMA Insights
Clinical Update
August 19, 2019

Adult Immunization Update

Author Affiliations
  • 1Rush University Medical Center, Division of Infectious Diseases, Chicago, Illinois
JAMA. 2019;322(11):1096-1097. doi:10.1001/jama.2019.12739

Immunization guidelines for adults are routinely updated, and primary care clinicians should be aware of the most current immunization recommendations. Within the past 2 years, 2 new vaccines were approved by the US Food and Drug Administration (FDA) for adults. These include Shingrix, a herpes zoster vaccine containing a specific protein subunit of the virus (recombinant glycoprotein E) with a novel adjuvant (an added substance that enhances or prolongs the immunologic response), and Heplisav-B, a single-antigen recombinant hepatitis B vaccine with a novel adjuvant. The eTable in the Supplement details the Advisory Committee on Immunization Practices (ACIP) 2019 immunization schedule for adults by age group.1

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