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Comment & Response
September 17, 2019

Catheter Ablation Compared With Drug Therapy for Atrial Fibrillation

Author Affiliations
  • 1Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
JAMA. 2019;322(11):1105-1106. doi:10.1001/jama.2019.10684

To the Editor Dr Packer and colleagues for the CABANA Investigators demonstrated no significant difference between catheter ablation and antiarrhythmic drug therapy in patients with paroxysmal and persistent atrial fibrillation on the composite primary end point of death, disabling stroke, serious bleeding, or cardiac arrest.1 For the composite secondary end point of death or CV hospitalization, patients randomized to catheter ablation had better event-free survival than those randomized to antiarrhythmic drugs.