To the Editor Dr Packer and colleagues for the CABANA Investigators demonstrated no significant difference between catheter ablation and antiarrhythmic drug therapy in patients with paroxysmal and persistent atrial fibrillation on the composite primary end point of death, disabling stroke, serious bleeding, or cardiac arrest.1 For the composite secondary end point of death or CV hospitalization, patients randomized to catheter ablation had better event-free survival than those randomized to antiarrhythmic drugs.
Wang NC. Catheter Ablation Compared With Drug Therapy for Atrial Fibrillation. JAMA. 2019;322(11):1105–1106. doi:10.1001/jama.2019.10684
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