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Comment & Response
September 17, 2019

Optimal Gestational Weight Gain—Reply

Ellis Voerman, MSc1; Vincent W. V. Jaddoe, MD, PhD1; Romy Gaillard, MD, PhD1; et al on behalf of the LifeCycle Project-Maternal Obesity and Childhood Outcomes Study Group
Author Affiliations
  • 1Department of Pediatrics, Erasmus MC, University Medical Center, Rotterdam, the Netherlands
JAMA. 2019;322(11):1107-1108. doi:10.1001/jama.2019.10950

In Reply Dr Bodnar and colleagues question the use of a composite outcome based on equally weighted outcomes in our study on the associations of gestational weight gain with adverse maternal and infant outcomes1 because the individual outcomes are associated with gestational weight gain in different directions and might vary in importance. We do not consider the different directions of the associations problematic because the simultaneous inclusion of the outcomes in the composite reflects the fact that optimal gestational weight gain is a trade-off between outcomes occurring at both low and high levels of gestational weight gain.