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Comment & Response
September 24, 2019

Publication Bias in Trials With and Without Null Findings—Reply

Author Affiliations
  • 1Computational Behavioral Science Laboratory, Northeastern University, Boston, Massachusetts
  • 2Department of Pediatrics, University of California, San Francisco
  • 3Department of Psychiatry, University of California, San Francisco
JAMA. 2019;322(12):1214. doi:10.1001/jama.2019.11144

In Reply Drs Cristea and Gentili raise some useful considerations related to our research letter.1 Our work addressed a single potential source of publication bias: how do RCTs that accept or reject a null hypothesis for the primary outcome compare on simple publicly available measures of “high impact”? Finding no difference between these postpublication metrics should not be read as an obviation of publication biases more generally.