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Comment & Response
October 1, 2019

Metformin for Type 2 Diabetes—Reply

Author Affiliations
  • 1Endocrinology Service, Memorial Sloan Kettering Cancer Center, New York, New York
  • 2Section of Endocrinology, Yale School of Medicine, New Haven, Connecticut
JAMA. 2019;322(13):1313. doi:10.1001/jama.2019.11505

In Reply In their letter regarding our JAMA Insights Clinical Update article,1 Dr Caturano and colleagues point out several additional considerations in prescribing metformin. These include comparable or superior glucose-lowering efficacy compared with most alternatives, as well as evidence for safety and efficacy in pediatric and older patients with diabetes.