In Reply In their letter regarding our JAMA Insights Clinical Update article,1 Dr Caturano and colleagues point out several additional considerations in prescribing metformin. These include comparable or superior glucose-lowering efficacy compared with most alternatives, as well as evidence for safety and efficacy in pediatric and older patients with diabetes.
Flory J, Lipska K. Metformin for Type 2 Diabetes—Reply. JAMA. 2019;322(13):1313. doi:10.1001/jama.2019.11505
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