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Research Letter
October 8, 2019

Exercise Heat Stress in Patients With and Without Type 2 Diabetes

Author Affiliations
  • 1Human and Environmental Physiology Research Unit, University of Ottawa, Ottawa, Ontario, Canada
  • 2Department of Medicine, University of Calgary, Calgary, Alberta, Canada
  • 3FAME Laboratory, University of Thessaly, Trikala, Greece
  • 4Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba City, Japan
JAMA. 2019;322(14):1409-1411. doi:10.1001/jama.2019.10943

Performing exercise in the heat can increase the risk of health complications, especially among middle-aged and older adults who have impaired whole-body heat loss (WBHL) relative to young adults.1 That risk may be higher among patients with type 2 diabetes due to abnormalities in cutaneous vasodilation and sweating, which facilitate WBHL.2 However, repeated brief exercise for 7 days or more during heat exposure (heat acclimation) may mitigate this risk by enhancing WBHL.3 We therefore assessed whether type 2 diabetes impairs heat loss in physically active middle-aged and older adults during exercise heat stress and whether heat acclimation could offset any impairment.

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