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August 4, 1945

MULTIPLE CARCINOMAS

JAMA. 1945;128(14):1046. doi:10.1001/jama.1945.02860310060024

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Abstract

To the Editor:—  In the clinical note by Dr. C. A. Holland of Philadelphia in The Journal, June 2, appears the following paragraph:Irradiation was administered by Dr. Edward Chamberlain between June 10 and July 18, five days a week in daily dosages of 100 roentgens (one fourth in each of four positions: anteroposterior, posteroanterior, left posterior oblique and right posterior oblique) to a total of 3,000 roentgens. This heavy dosage was well tolerated, with a minimum of skin reaction.Unfortunately this paragraph does not truly set forth the essential factors that were used in the x-ray treatment of this remarkable case. In reading Dr. Holland's description of the therapy technic, one would naturally understand that each of the four skin portals received one fourth of 3,000 roentgens. Actually each of the four skin portals received 3,000 roentgens. On each of the thirty days on which treatments were administered the

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