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October 22/29, 2019

Cervical Cancer as a Global Concern: Contributions of the Dual Epidemics of HPV and HIV

Author Affiliations
  • 1Division of Global Women’s Health, Department of Obstetrics and Gynecology, University of North Carolina School of Medicine, Chapel Hill
  • 2Clinical HIV Research Unit, Department of Medicine, University of the Witwatersrand Faculty of Health Sciences, Johannesburg, South Africa
JAMA. 2019;322(16):1558-1560. doi:10.1001/jama.2019.16176

Cancer of the uterine cervix is among the most preventable human malignancies,1,2 yet it remains a leading cause of death among women worldwide, accounting for more than 300 000 deaths annually.3 Well on its way to elimination in the global north, cervical cancer mostly affects women living in low- or middle-income countries (LMICs), where limited access to vaccination, screening, and therapy have made it overwhelmingly a disease of women who are poor and lack access to health care. Nowhere is this more evident than in sub-Saharan Africa, where HIV is endemic and where cervical cancer has surpassed breast cancer as the most common and deadly cancer in women.3