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August 11, 1945

THE TREATMENT OF IMPETIGO CONTAGIOSA WITH SULFATHIAZOLE IN AN ALCOHOLIC PLASTIC VEHICLE

JAMA. 1945;128(15):1096-1098. doi:10.1001/jama.1945.92860320002011a
Abstract

The treatment of impetigo contagiosa has always been an acute problem particularly in children, owing to the extreme contagiousness of the disease. This disease has been reported among war refugees1 and has recently assumed military importance.2

The etiology of impetigo is somewhat obscure and there is no uniform agreement regarding the agent responsible for the disease. Some3 regard the streptococcus as the etiologic agent, others4 believe a virus responsible, but the more general opinion5 is that staphylococci, so prevalent in the lesions, are responsible for the disease. In spite of the fact that reinfection is common among children, one of us (Pijoan) was unable to infect himself with material from impetiginous lesions in various stages of development.

The methods of treating impetigo have been extensive. To the lesions have been applied tinctures of mercurial disinfectants, copper sulfate-zinc,6 solutions of ferric chloride,7 boric acid-zinc ointment,8 staphylococcus toxoid,9 silver nitrate

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