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November 5, 2019

Bioinspired Adhesive Dressing Actively Heals Wounds in Animals

JAMA. 2019;322(17):1642-1643. doi:10.1001/jama.2019.16734

To create a novel wound adhesive that accelerates wound healing, scientists recently drew inspiration from embryonic processes that pull wound edges together like a purse-string to regenerate fetal skin without inflammation or scarring.

In research described in Science Advances, investigators designed what they called active adhesive dressings (AADs) that exert contractile forces sufficient to promote active wound closure. Gauzes, cotton wools, and dressings conventionally used to treat skin injuries rely on slow and passive healing processes, which can be insufficient when caring for certain traumatic injuries, chronic wounds, and aging populations with diminished wound-healing ability.

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