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JAMA Clinical Guidelines Synopsis
November 4, 2019

Medical Management of Opioid-Induced Constipation

Author Affiliations
  • 1Section of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois
  • 2Section of General Internal Medicine, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois
JAMA. Published online November 4, 2019. doi:https://doi.org/10.1001/jama.2019.15852

Opioid pain medications are frequently used to treat acute and chronic pain and have had a major increase in use over the last 2 decades, particularly for noncancer pain. In 2017, there were 58 opioid prescriptions written for every 100 people in the United States. An estimated 17% of the US population has had at least 1 opioid prescription filled, although there is some uncertainty about this estimate because of illicit and nonprescription use.1

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