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Biotech Innovations
November 12, 2019

Supercooling Triples Liver Preservation Time

JAMA. 2019;322(18):1756. doi:10.1001/jama.2019.17613

Scientists have preserved human organs at subzero temperatures for the first time, potentially widening the window of opportunity for transplants. A technique called supercooling tripled the amount of time that human livers can be preserved without damage.

Currently, donor organs can be stored safely on ice for up to 9 hours on average in a preservation solution ranging from 4°C to 8°C. Lower temperatures preserve organs longer but essentially cause frostbite, rendering them unusable. Supercooling solves this problem by preventing organs from freezing in subzero temperatures.