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Research Letter
November 12, 2019

Immunization Status at the Time of Liver Transplant in Children and Adolescents

Author Affiliations
  • 1Section of Gastroenterology, Hepatology, and Nutrition, University of Colorado, Denver, Aurora
  • 2Adult and Child Consortium for Health Outcomes Research and Delivery Science (ACCORDS), University of Colorado, Denver, Aurora
  • 3Section of Pediatric Infectious Diseases, University of Colorado, Denver, Aurora
JAMA. 2019;322(18):1822-1824. doi:10.1001/jama.2019.14386

Vaccine-preventable infections are a serious complication following transplant. In a multicenter retrospective cohort study of 6980 pediatric solid organ transplant recipients between 2004 and 2011, 15.6% were hospitalized with a vaccine-preventable infection in the first 5 years after transplant at a rate of up to 87 times higher than in the general pediatric population.1 Immunizations are a minimally invasive, cost-effective way to reduce the incidence of these infections. We quantified the percentage of patients at Society of Pediatric Liver Transplantation centers who were up to date for their age on immunizations at the time of transplant and determined whether demographic and clinical factors were associated with immunization status at the time of transplant.