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November 8, 2019

Predicting Risk of Kidney Disease: Is Risk-Based Kidney Care on the Horizon?

Author Affiliations
  • 1Kidney Health Research Collaborative, University of California, San Francisco and San Francisco VA Health Care System, San Francisco
JAMA. 2019;322(21):2079-2081. doi:10.1001/jama.2019.17378

Chronic kidney disease (CKD) causes an enormous human and financial toll worldwide. In the United States alone, an estimated 37 million persons have CKD, and its incidence globally is rising.1,2 Patients with CKD are at incrementally increased risk for major cardiovascular events as their disease progresses,3 and several million will progress to kidney failure.4 Early, effective management of risk factors, such as hypertension and diabetes, is imperative to prevent the development of CKD and its related adverse consequences, yet less than half of patients with hypertension in the United States attain recommended blood pressure targets.5 An accurate tool that identifies persons at elevated risk of developing CKD may facilitate efforts to modify relevant risk factors and could be used to determine the frequency of kidney health monitoring among persons at risk of CKD.