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August 25, 1945

Penicillin Therapy Including Tyrothricin and Other Antibiotic Therapy

JAMA. 1945;128(17):1258. doi:10.1001/jama.1945.02860340064026

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This monograph constitutes an attempt to correlate the available information on penicillin and other antibiotic agents for the medical and dental professions. With more and more penicillin becoming available for clinical use and with an expanding interest being manifested in antibiotics, such a review is timely. Kolmer has compressed much useful information within the covers of this compact volume. The first half of the monograph is devoted to the basic principles of therapy with antibiotics, with emphasis being placed on penicillin. The section on the principles of penicillin therapy summarizes the present status of the subject very well. In the sections devoted to the clinical use of penicillin for specific infectious diseases some of the recommendations will not be generally accepted. As an example, in the treatment of staphylococcic septicemia Kolmer advises that sulfathiazole should be administered simultaneously with penicillin. It remains to be proved whether this routine therapeutic combination

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