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February 13, 1937

Undersøgelser over Refektion, med særlight Henblik paa Stivelsens Forhold

JAMA. 1937;108(7):583. doi:10.1001/jama.1937.02780070067030

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The term refection refers to a condition that occasionally appears in experimental animals, mainly rats, fed on diets devoid of or poor in vitamin B and characterized by normal growth in spite of the insufficient nourishment and the excretion of bulky white feces containing large amounts of undigested starch. Refection may occur spontaneously or be produced by the feeding of feces from other refected animals. The stool contains characteristic gram-negative vibrios, amylase and starch which is not digested by ptyalin. The amount of starch in the stool is between 60 and 85 per cent in proportion to the amount of dry substance, and the utilization of starch is 57 to 92.4 per cent. Most of the starch escapes digestion in the small intestine. The possibilities are suggested that the reduced digestibility is due to changes in the starch grain itself and that the dyspepsia which results from the low or

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