The 2 most common causes of death in the United States are cancer and heart disease. Screening, defined as the process of proactively identifying disease risk, is pursued as part of routine medical care of adults. Standardized imaging-based screening (eg, mammography), procedure-based screening (eg, colonoscopy), and laboratory-based screening (eg, measurement of blood cholesterol levels) exist for cancer and heart disease; however, there is not currently any recommended use of DNA-based screening in these disease areas.
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Murray MF, Evans JP, Khoury MJ. DNA-Based Population Screening: Potential Suitability and Important Knowledge Gaps. JAMA. 2020;323(4):307–308. doi:10.1001/jama.2019.18640
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