[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 34.204.191.0. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Views 7,430
Citations 0
Viewpoint
December 6, 2019

DNA-Based Population Screening: Potential Suitability and Important Knowledge Gaps

Author Affiliations
  • 1Department of Genetics, Yale School of Medicine, New Haven, Connecticut
  • 2Department of Genetics, University of North Carolina at Chapel Hill
  • 3Office of Genomics and Precision Public Health, Centers for Disease Control and Prevention, Atlanta, Georgia
JAMA. 2020;323(4):307-308. doi:10.1001/jama.2019.18640

The 2 most common causes of death in the United States are cancer and heart disease. Screening, defined as the process of proactively identifying disease risk, is pursued as part of routine medical care of adults. Standardized imaging-based screening (eg, mammography), procedure-based screening (eg, colonoscopy), and laboratory-based screening (eg, measurement of blood cholesterol levels) exist for cancer and heart disease; however, there is not currently any recommended use of DNA-based screening in these disease areas.

Limit 200 characters
Limit 25 characters
Conflicts of Interest Disclosure

Identify all potential conflicts of interest that might be relevant to your comment.

Conflicts of interest comprise financial interests, activities, and relationships within the past 3 years including but not limited to employment, affiliation, grants or funding, consultancies, honoraria or payment, speaker's bureaus, stock ownership or options, expert testimony, royalties, donation of medical equipment, or patents planned, pending, or issued.

Err on the side of full disclosure.

If you have no conflicts of interest, check "No potential conflicts of interest" in the box below. The information will be posted with your response.

Not all submitted comments are published. Please see our commenting policy for details.

Limit 140 characters
Limit 3600 characters or approximately 600 words
    ×