Patients with familial hypercholesterolemia who took a statin in childhood had a lower risk of cardiovascular disease (CVD), reported a 20-year follow-up study in the New England Journal of Medicine.
The follow-up study examined cardiovascular outcomes from 184 of 214 patients with familial hypercholesterolemia who participated in the original placebo-controlled trial evaluating 2-year pravastatin efficacy and safety. Participants began taking the statin when they were between 8 and 18 years old; the mean age at follow-up was 31.7 years. The investigators compared cardiovascular events between the now adult participants and their affected parents, for whom statins weren’t available until later in life.
Slomski A. Statins in Childhood May Reduce CVD From Familial Hypercholesterolemia. JAMA. 2019;322(24):2375. doi:10.1001/jama.2019.20564
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