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February 27, 1937


JAMA. 1937;108(9):717-718. doi:10.1001/jama.1937.92780090001009

The development of nervous complications and sequelae in acute infections in childhood is always of interest and concern to the neurologist and the pediatrician. On account of the inherent instability of the central nervous system in the young, its vulnerability, and reaction to toxic substances is very much enhanced. This fact is a common observation clinically and one notes all forms of abnormal neural manifestations in the wake of toxic invasion of whatever type.

The exanthems in particular contribute a goodly share of these neural disturbances, and measles "encephalitis" is pretty well known and recognized by the profession. Other forms and combinations, affecting single or multiple parts of the central nervous system, each registering in its own particular manner interference with function, are seen from time to time, although the incidence is very low.

Thus, according to Rolleston,1 "encephalitis" occurs in measles more commonly than after any of the