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September 15, 1945


JAMA. 1945;129(3):230-231. doi:10.1001/jama.1945.02860370052024

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To the Editor:—  In the paper on "Hepatitis Following Blood or Plasma Transfusions" by Capt. E. M. [ill] [ill]ppaport in the issue of July 28 it is stated that those blood donors in the preicteric stage or with hepatitis without obvious jaundice constitute the greatest menace as propagators of hepatitis. It is further stated that "in view of the widespread incidence of infectious hepatitis a transient healthy carrier state might exist among some volunteer blood donors and detection of such depositors would be impossible."For the detection of those in the preicteric stage, the following suggestions were made: (1) "Recording the lot number of each flask of plasma at the time of its use, thus permitting ultimate withdrawal of contaminated batches"; (2) "that quantitative bilirubin determinations be performed routinely on all patients who have received plasma or blood from doubtful sources at monthly intervals from the third to the sixth

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