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September 22, 1945


JAMA. 1945;129(4):250-257. doi:10.1001/jama.1945.02860380008003

My object in this presentation is to demonstrate the advantages of the Barach aerosol penicillin method1 as an effective, inexpensive means of treatment which eliminates some of the present difficulties of penicillin administration. It makes penicillin therapy readily available to the general practitioner in the office and to the patient in the home. The particular value of the technic in upper respiratory infections is emphasized, since a large proportion of conditions for which penicillin is required in general practice are the acute bacterial invasions and chronic bacterial infections of the upper respiratory tract which develop into parasitic states.2 In many of these cases it appears to be more efficient than the parenteral method.

The preeminent value of parenteral penicillin therapy in many infections and its freedom from severe reactions have now been established by a mass of clinical evidence. The only real disadvantage found in penicillin treatment has