Prior to Sept. 18, 1944 the treatment of acute thyroiditis had in our experience been unsatisfactory. On that date a young woman with the outward appearance of good health, the wife of a physician, presented herself at our office with the following history: She had enjoyed good health all her life except for diseases of childhood. She had had no recent infection. One week before, her thyroid gland had become swollen and quite sensitive to pressure. The gland was somewhat painful on swallowing. Generally she had not felt well, was more nervous, was rather irritable and had a tendency to increased perspiration. She had been more conscious of her heart action and had a moderate elevation of temperature. She thus complained of the general symptoms of a mild infectious process.
Physical examination revealed that the patient was apparently of good nutrition and good color. The only important findings were an
KING BT, ROSELLINI LJ. TREATMENT OF ACUTE THYROIDITIS WITH THIOURACIL: PRELIMINARY REPORT. JAMA. 1945;129(4):267–268. doi:10.1001/jama.1945.02860380025006
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