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Clinical Trials Update
January 28, 2020

Testosterone Improved Body Composition in Male Cancer Survivors

JAMA. 2020;323(4):301. doi:10.1001/jama.2019.22086

Male cancer survivors aged 25 through 50 years who received testosterone replacement had decreased body fat and increased muscle mass in a PLOS Medicine trial.

The study included 136 male survivors of testicular cancer, lymphoma, and leukemia who had borderline low testosterone (7–12 nmol/L). Participants were randomly assigned to receive testosterone (Tostran 2% gel) or placebo for 26 weeks.