Urinary tract infections (UTIs) disproportionately affect adult women. Postmenopausal women are especially vulnerable to recurrent UTI, commonly defined as culture-proven UTIs that have occurred at least twice within 6 months or 3 times within 12 months. Current prevalence estimates are lacking, despite the significant negative effect of recurrent UTI on quality of life and health care costs.1 There is significant variation in patient care related to inconsistent recommendations from key professional societies due to lack of high-quality evidence supporting clinical guidelines.2-5