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September 29, 1945


JAMA. 1945;129(5):350-351. doi:10.1001/jama.1945.02860390036012

According to Blake, Maxcy and their colleagues,1 the term tsutsugamushi disease is, on the basis of priority, appropriate to describe the condition which is also commonly known as scrub typhus or mite-borne typhus. The causative organism is Rickettsia orientalis and this name has the best claim to recognition. After thorough evaluation of the evidence, these investigators conclude that the disease, originally known as tsutsugamushi by the Japanese, is not confined to the river valleys of the islands of Honshu, Formosa and the Pescadores but has been reported from many localities in southeastern Asia and the adjacent islands in the Indian Ocean and southwest Pacific and in the coastal area of North Queensland.

Although there is some variation in clinical manifestations of the disease, particularly with regard to the frequency with which the primary lesion, or eschar, is found and the severity or case fatality rate, these variations are not