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October 6, 1945

SKIN DIABETES: HYPERGLYCODERMIA WITHOUT HYPERGLYCEMIA

JAMA. 1945;129(6):438-440. doi:10.1001/jama.1945.02860400022007
Abstract

Dermatologists have long been acquainted with the fact that the institution of a diabetic diet often brings strikingly good results in therapy resistant cases, notably of dermatitis, furunculosis and pruritus, especially in elderly, obese individuals with a purplish red complexion; and that this is true despite the fact that the fasting blood not infrequently reveals normal levels, and the urine is negative as to sugar. Several years ago, in dealing with cases of this kind, on observing a striking rise in the skin sugar levels without a similar increase in the blood sugar, I1 suggested the term "independent cutaneous glycohistechia"2 to designate the rise in the skin sugar alone. In view of the fact that in these patients diabetic management served to bring the skin sugar levels down to normal and to clear up the skin condition and that a diet rich in carbohydrates brought on a recurrence

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