Primary hyperparathyroidism (PHPT) is a common disorder of dysregulated calcium homeostasis. In 2013, its incidence in the US is estimated at 66 per 100 000 person-years among women and 25 per 100 000 among men.1 The adoption of routine chemistry panel testing in the 1970s led to increased discovery of PHPT and changed its clinical presentation in developed nations from a rare, highly symptomatic disease to a milder, more subtle condition.
Zhu CY, Sturgeon C, Yeh MW. Diagnosis and Management of Primary Hyperparathyroidism. JAMA. 2020;323(12):1186–1187. doi:10.1001/jama.2020.0538
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